Avène , for the care of sensitive skin, is based on the calming properties of Thermal Water. Attentive to studies on the beneficial effects of Thermal Water on skin problems, Pierre Fabre bought the Avène thermal spa in 1975 and established a vast research program on Avène Thermal Water. In 2001, Avène Cicalfate was born, the product most prescribed by dermatologists today. the range Avène Xeracalm , specific for itching and Avène Cleanance , for acne, are other top sellers.